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RECRUITING
NCT06802354
PHASE3

Efficacy of Ozone Therapy in Reducing Complications Following Impacted Mandibular Third-molar Surgery

Sponsor: Jelena Krunic

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if use of ozone works to treat complications after impacted mandibular third molar surgery. It will also learn does ozone has positive effect on wound healing and quality of life. The main questions it aims to answer are: * Does ozone reduce incidence of postoperative compliactions such as pain, swelling or reduced mouth opening after impacted mandibular third molar surgery? * Does ozone improve wound healing after impacted mandibular third molar surgery? * Does ozone have positive effect on quality of life after impacted mandibular third molar surgery? Participants will: * Receive ozone after impacted mandibular third molar surgery. * Visit the clinic 1st, 3rd, and 7th days after the intervention for checkups and tests. * Keep a diary of their symptoms.

Official title: Application of Gaseous Ozone in the Surgical Extraction of Impacted Mandibular Third Molars: Impact on the Incidence of Postoperative Complications and Healing Processes

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2024-12-01

Completion Date

2025-05

Last Updated

2025-01-31

Healthy Volunteers

No

Interventions

DRUG

Ozone

In Ozone group, ozone will be applied at the site of the extraction wound for 30 seconds after the surgical extraction of the third molar, according to the manufacturer's recommendation for wound treatment following tooth extraction.

DRUG

Placebo

In the control group, a sham ozone therapy will be applied at the site of the extraction wound for 30 seconds after the surgical extraction of the third molar .

Locations (1)

University of East Sarajevo, Faculty of Medicine

Foča, Republika Srpska, Bosnia and Herzegovina