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Effects of LH and FSH on Metabolic Regulation in Cumulus Cells
Sponsor: Kaohsiung Veterans General Hospital.
Summary
The combined use of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) has improved IVF pregnancy rates in infertile women aged 35-40, but its mechanisms remain unclear. This prospective study will examine how FSH and LH combined treatment affects cumulus cell energy metabolism. Sixty participants will be divided into two groups receiving either combined therapy or FSH alone. The study will analyze patient characteristics, infertility history, and compare mitochondrial function in cumulus cells to evaluate treatment effectiveness.
Official title: Investigation of the Combined Effects of Luteinizing Hormone and Follicle-Stimulating Hormone on Metabolic Regulation in Cumulus Cells
Key Details
Gender
FEMALE
Age Range
35 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-12-01
Completion Date
2027-12-31
Last Updated
2025-01-31
Healthy Volunteers
No
Conditions
Interventions
FSH and LH
In the study group, participants receive FSH and LH in IVF cycle
FSH
In the control group, participants receive FSH alone in IVF cycle
Locations (1)
Kaohsiung Veterans General Hospital
Kaohsiung City, Taiwan