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Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management
Sponsor: Osoian Cristiana
Summary
This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery. Additionally, the study will objectively evaluate using NOL how intravenous lidocaine administration, influences opioid requirements and the effect of this multimodal approach on early postoperative outcomes. The investigators hypothesize that NOL-guided intraoperative opioid administration reduces both intraoperative and postoperative opioid use, positively influencing 24-hour outcomes. Furthermore, the addition of intraoperative lidocaine in NOL-guided analgesia may further decrease opioid consumption.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2023-05-18
Completion Date
2026-02-01
Last Updated
2025-02-03
Healthy Volunteers
No
Conditions
Interventions
Lidocaine Intravenous Infusion
intravenous lidocaine 10 mg/ml continuous infusion
NOL
Intraoperative Nociception Level index monitoring and guided analgesia
Locations (1)
Regional Gastroenterology and Hepatology Institute Octavian Fodor
Cluj-Napoca, Cluj, Romania