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RECRUITING
NCT06805253

Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

Sponsor: Petrovsky National Research Centre of Surgery

View on ClinicalTrials.gov

Summary

Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume overload and this fact plays positive role in early-stage post-operative left ventricle volume and function recovery. LV volume, systolic and diastolic function will be monitored with echocardiography (EchoCG) along with life quality in patients with different grades of functional mitral regurgitation secondary to severe chronic aortic insufficiency after surgical treatment of aortic regurgitation.

Official title: Left Ventricular Reverse Remodeling Outcomes Evaluation in Patients With Aortic Regurgitation After Surgical Treatment

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

120

Start Date

2024-05-09

Completion Date

2030-05

Last Updated

2025-06-11

Healthy Volunteers

No

Interventions

OTHER

Not applicable - observational study

observation only

Locations (2)

Petrovsky National Research Center of Surgery

Moscow, Russia

Voronezh Regional Clinical Hospital No. 1

Voronezh, Russia