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Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation
Sponsor: Petrovsky National Research Centre of Surgery
Summary
Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume overload and this fact plays positive role in early-stage post-operative left ventricle volume and function recovery. LV volume, systolic and diastolic function will be monitored with echocardiography (EchoCG) along with life quality in patients with different grades of functional mitral regurgitation secondary to severe chronic aortic insufficiency after surgical treatment of aortic regurgitation.
Official title: Left Ventricular Reverse Remodeling Outcomes Evaluation in Patients With Aortic Regurgitation After Surgical Treatment
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
120
Start Date
2024-05-09
Completion Date
2030-05
Last Updated
2025-06-11
Healthy Volunteers
No
Conditions
Interventions
Not applicable - observational study
observation only
Locations (2)
Petrovsky National Research Center of Surgery
Moscow, Russia
Voronezh Regional Clinical Hospital No. 1
Voronezh, Russia