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Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing
Sponsor: Harvard Pilgrim Health Care
Summary
Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the U.S. initiative to end the HIV epidemic, but healthcare providers lack tools to support PrEP discussions and prescribing for patients likely to benefit. This research will evaluate whether integrating automated tools into electronic health records to help providers efficiently and equitably identify potential candidates for PrEP, discuss PrEP, and prescribe PrEP can improve PrEP initiation and persistence in safety-net community health centers. It will achieve this by conducting a stepped-wedge trial of a decision support tool with an embedded HIV prediction model to identify patients likely to benefit from PrEP. The intervention will be delivered to healthcare providers in 16 community health centers within the national OCHIN network.
Official title: Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing in Community Health Centers
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2025-04-21
Completion Date
2030-07
Last Updated
2025-04-24
Healthy Volunteers
No
Conditions
Interventions
Predictive Analytics and Clinical Decision Support
The intervention will include automated EHR notifications to clinicians at 16 OCHIN community health centers about patients who are likely to benefit from PrEP. These patients will be identified by an HIV prediction model that was developed and validated during the pilot phase of this study using historical OCHIN EHR data. For patients above a preselected threshold of predicted HIV risk, clinicians will be notified at the point of care that the patient may benefit from PrEP and will be provided with EHR-based tools to support discussions and prescribing. The intervention will also include coaching on PrEP and the decision support tool, as well as project team support during the trial period.
Locations (16)
Bay Area Community Health Liberty Clinic
Fremont, California, United States
Lifelong East Oakland Health Center
Oakland, California, United States
TrueCare Oceanside Family Medicine
Oceanside, California, United States
DAP Legacy
Palm Springs, California, United States
One Community Health Midtown Campus
Sacramento, California, United States
Southwest Community Health Center 968 Fairfield Avenue
Bridgeport, Connecticut, United States
Mercy Care Decatur Street
Atlanta, Georgia, United States
Siouxland Community Health Center Sioux City
Sioux City, Iowa, United States
Lynn Community Health Center 269 Union
Lynn, Massachusetts, United States
Mattapan Community Health Center Blue Hill
Mattapan, Massachusetts, United States
Neighborhood Family Practice Ridge Community Health Center
Cleveland, Ohio, United States
Signature Health Painesville
Painesville, Ohio, United States
Variety Care Sequoyah
Oklahoma City, Oklahoma, United States
Prism Belmont
Portland, Oregon, United States
Bee Busy Wellness Center Bray Oaks
Houston, Texas, United States
Seattle Roots Community Health Carolyn Downs Community Clinic
Seattle, Washington, United States