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Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
Sponsor: Skolkovo Institute of Science and Technology
Summary
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy (fNIRS) in patients with hemiparesis after stroke. Participants in the study performed a simple stimulus-response task several times with one healthy and one paralyzed limb at different stages of basic rehabilitation. A group of healthy, age-matched volunteers participated in the same experiment to verify the stroke-related changes. The researchers recorded fNIRS signals, muscle activity using electromyography, and heart activity using electrocardiography.
Official title: Studying the Mechanisms of Visual-motor Transformation to Find Neurophysiological Markers of Altered Functions of Cortical Motor Circuits in Patients with Neurological Disorders and Developing Technologies for Their Rehabilitation.
Key Details
Gender
All
Age Range
35 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2024-06-26
Completion Date
2025-04
Last Updated
2025-02-04
Healthy Volunteers
Yes
Interventions
Stimulus response task
Participants were tasked with performing a finger extension exercise that required pressing buttons in response to visual stimuli. In cases where physical movement was not possible, participants were instructed to imagine performing the task while focusing on their fingers.
Locations (2)
Skolkovo Institute of Science and Technology (Skoltech)
Moscow, Russia
Skolkovo Institute of Science and Technology (Skoltech)
Moscow, Russia