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RECRUITING
NCT06808685

Real World Multicenter National Study to Evaluate the Effectiveness and Safety of Biosimilar Bevacizumab Elovie

Sponsor: Libbs Farmacêutica LTDA

View on ClinicalTrials.gov

Summary

Colorectal cancer is one of the most common tumors and is the second most prevalent cause of cancer death, leading to almost 1 million deaths per year.Elovie is a bevacizumab biosimilar medicine marketed by Libbs Farmacêutica, which had its registration approved by ANVISA in May 2022.At the time of registration a robust evidence package was presented that included, for example, pharmacokinetic bioequivalence studies in patients with metastatic RCC (mRCC) and a phase III study in participants with non-small cell lung cancer .Conducting a real-world study to evaluate the effectiveness and safety of bevacizumab biosimilar Elovie in patients with mCRC is crucial to provide relevant information on how this therapy behaves in real-world clinical conditions in brazilian population.

Official title: Real-world Multicenter National Study to Evaluate the Effectiveness and Safety of Biosimilar Bevacizumab Elovie in First-line Treatment in Participants With Unresectable Metastatic Colorectal Cancer

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

133

Start Date

2025-06-01

Completion Date

2027-11-30

Last Updated

2026-06-01

Healthy Volunteers

No

Locations (14)

Unimed Vitória

Vitória, Espírito Santo, Brazil

Centro de Oncologia do Paraná (COP)

Curitiba, Paraná, Brazil

Centro de Pesquisa Unimed Londrina

Londrina, Paraná, Brazil

Instituto Dor de Pesquisa E Ensino

Recife, Pernambuco, Brazil

Centro de Ensino e Pesquisa - Hospital São Marcos

Teresina, Piauí, Brazil

Centro de Pesquisa Unimed Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil

Associação Hospitalar Moinhos de Vento

Porto Alegre, Rio Grande do Sul, Brazil

Unidade de Ensino e Pesquisa UEP-COHM

Santo Ângelo, Rio Grande do Sul, Brazil

OncoJaraguá

Jaraguá do Sul, Santa Catarina, Brazil

Hospital Vera Cruz

Campinas, São Paulo, Brazil

CEON+ Pesquisas

São Caetano do Sul, São Paulo, Brazil

COE Ensino e Pesquisa

São José dos Campos, São Paulo, Brazil

Centro Paulista de Oncologia

São Paulo, São Paulo, Brazil

Instituto Dor de Pesquisa E Ensino

São Paulo, São Paulo, Brazil