Clinical Research Directory

Inclusion Criteria: * Age ≥18 years, * Anticipated waitlisting for LT, * Speaks the Dutch language, * Understands the purpose of the study and has given written informed consent. Exclusion Criteria: * Experienced a major adverse cardiovascular event in the past six months, * Experienced a cerebrovascular incident in the past six months, * Medical history of an uncontrolled heart rhythm disorder, * Hepatic encephalopathy grade 3 or 4, * Acute liver failure, * Acute-on-chronic liver failure, * Hospitalization at start of the study. * Non-treated esophageal varices (i.e., no previous variceal eradication endoscopy or adequately dosed NSBB)