Clinical Research Directory

Inclusion Criteria: 1. Signed informed consent prior to participation in the study. 2. Age ≥ 18 years. 3. Patient has at least one intrabronchial, near-to-airway located or peripheral pulmonary nodule - with or without pathological lymph nodes - which is considered malignant (independent of its primary origin). 4. Patient is considered fit to undergo a diagnostic and/or therapeutic bronchoscopy (with or without addition of virtual navigation and/or endobronchial ultrasound; including propofol sedation or general anesthesia if either is indicated) to obtain tumor material according to standard care protocols. Exclusion Criteria: 1. History of infusion reactions to bevacizumab. 2. Medical or psychiatric conditions that compromise the patient's ability to give informed consent. 3. Pregnancy or breast feeding.