Clinical Research Directory

Inclusion Criteria: * Patients 18 years of age and older * Primary osteoarthritis diagnosis with indication for primary elective unilateral TKA * No previous contralateral knee injections (steroids/biologics) within one year of study * Not scheduled for bilateral TKA or a subsequent staged contralateral TKA within the next six months * No previous or active infection or trauma (osseous/ligamentous/extensor mechanism) on the contralateral knee * Contralateral knee pain \& symptoms - defined as a VAS of \>4/10 at initial pre-op visit * Contralateral knee OA quantified as: Kellgren and Lawrence grade \>2-4 * Assessed by PI (AK) who will not be contributing any patients to the study through examination of blinded knee radiographs (3 views: AP/lateral/Sunrise) * Patient is able to read and understand English and provide informed consent to participation in the study Exclusion Criteria: * Other aetiologies of OA that warrants TKA (inflammatory or post traumatic arthritis) * Cognitive impairment (dementia, Alzheimer's, uncontrolled delirium) which will prevent patients from completing primary outcome measure or comply with follow-up requirements * Previous TKA or ORIF or nailing on either knee * Previous or active knee infection or extensor mechanism disruption * Previous arthroscopy on either knee * Medical contraindication to elective TKA surgery