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NOT YET RECRUITING
NCT06813014
PHASE4

Pharmacogenetics of Response to Sitagliptin (PRS)

Sponsor: University of Maryland, Baltimore

View on ClinicalTrials.gov

Summary

This is a research study to find out how different people respond to a medication called sitagliptin. Sitagliptin is an FDA approved medication that is used to treat diabetes. We are asking for healthy, non-diabetic volunteers to participate in this 7-week study. If you agree to participate, you will take part in 2 clinic visits that are 4-6 weeks apart. At the clinic visits you will have an oral glucose tolerance test (OGTT) and other blood tests to see how your body processes glucose (sugar). An OGTT is a test in which your drink glucose and then blood samples are taken afterward at specific time points to measure glucose and insulin in your blood. Each clinic visit will last about 5 hours.

Official title: Sitagliptin's Effects on Glucose-stimulated Insulin Secretion and Oral Glucose

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

400

Start Date

2026-12

Completion Date

2032-12

Last Updated

2026-02-18

Healthy Volunteers

Yes

Conditions

Interventions

PROCEDURE

Oral Glucose Tolerance Test

Three hour glucose tolerance test

Locations (1)

University of Maryland Amish Research Clinic

Lancaster, Pennsylvania, United States