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Comparison of Clomid and Lezra With Lezra for Ovulation Induction in Clomid Resistant PCOS Case
Sponsor: HITEC-Institute of Medical Sciences
Summary
Clomiphene citrate resistant i.e failure to ovulate after 6 cycles of ovulation induction effects 15-40% of patients with PCOS.Two treatment groups will be formed one recieving letrozole alone and another recieving CC and letrozole combined.Mature follicles and endometrial thickness will be checked by transvaginal ultrasound and results will be recorded.
Official title: A RCT Comparing the Effectiveness of a Combination Therapy of Lezra and Clomid Versus Lezra Alone for Inducing Ovulation in Women Diagnosed With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome
Key Details
Gender
FEMALE
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
42
Start Date
2024-06-07
Completion Date
2025-03
Last Updated
2025-02-06
Healthy Volunteers
Yes
Conditions
Interventions
Clomiphene Citrate and letrozole
clomiphene citrate 100mg once daily along with letrozole 5mg to one group and letrozole 5mg to second group
Locations (1)
HIT Hospital
Rawalpindi, Punjab Province, Pakistan