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NCT06814093

Robotic Versus Laparoscopic Surgery for Middle and Low Rectal Cancer: a Target Trial Emulation

Sponsor: Xu jianmin

View on ClinicalTrials.gov

Summary

This study aims to compare the effectiveness of robotic surgery versus laparoscopic surgery in treating low rectal cancer. While robotic surgery has gained popularity, there is limited long-term evidence regarding its outcomes. By using real-world data from a specialized multicenter colorectal cancer database in Shanghai, China, this retrospective cohort study will emulate the target trial to evaluate whether robotic surgery offers advantages over laparoscopic surgery. Key factors such as disease-free survival, locoregional recurrence, circumferential margin positivity, and postoperative complications will be examined. The goal is to provide stronger, evidence-based support for the clinical use of robotic surgery in treating low rectal cancer.

Official title: Robotic Versus Laparoscopic Surgery for Middle and Low Rectal Cancer: A Retrospective Cohort Study Emulating the Target Trial

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

2702

Start Date

2021-01-01

Completion Date

2025-04-30

Last Updated

2025-05-09

Healthy Volunteers

No

Conditions

Interventions

PROCEDURE

Robotic surgery

Robotic surgery for radical resection of middle and low rectal cancer

PROCEDURE

Laparoscopic surgery

Laparoscopic surgery for radical resection of middle and low rectal cancer

Locations (1)

Zhongshan Hospital, Fudan University, Shanghai, China

Shanghai, Shanghai Municipality, China