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Bacteriophage Therapy for Morganella Morganii Prosthetic Joint Infection
Sponsor: University of Calgary
Summary
This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of a bacteriophage drug product to treat and prevent the recurrence of a Morganella morganii prosthetic joint infection of the hip. The patient has exhausted all conventional therapies, both surgical and medical, at considerable detriment to their quality of life. The treatment involves 2 intra-articular injections of bacteriophages into the joint and surrounding area and 14 days of intravenous phage therapy. The goal is to eliminate the infection and prevent further complications, providing a potential new treatment avenue for patients with difficult-to-treat infections.
Key Details
Gender
FEMALE
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
1
Start Date
2025-03-26
Completion Date
2026-03
Last Updated
2025-06-12
Healthy Volunteers
No
Conditions
Interventions
phage therapy
Single anti-Morganella morganii bacteriophage drug product
Locations (1)
Foothills Medical Centre, University of Calgary
Calgary, Canada