Clinical Research Directory
Browse clinical research sites, groups, and studies.
Tissue Markers Predictive of Early Stenosis in the Arterovenous Fistula for Hemodialysis
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Summary
The study involves the recruitment of two populations. POPULATION 1 (surgical sample of excess venous segment): at least 75 consecutive patients, enrolled according to the inclusion criteria and subjected to first AVF surgery as part of the normal care pathway, at the Metropolitan Vascular Surgery Unit, Dir. Prof. Mauro Gargiulo of the S.Orsola-Malpighi University Hospital. POPULATION 2 (surgical sample of arterialized venous segment from removal of previous AVF): at least 75 consecutive patients, enrolled according to the inclusion criteria and subjected to reoperation for correction of complication and/or new AVF by proximalization, as part of the normal care pathway, at the Metropolitan Vascular Surgery Unit, Dir. Prof. Mauro Gargiulo of the S.Orsola-Malpighi University Hospital.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2020-03-18
Completion Date
2025-12-31
Last Updated
2025-02-07
Healthy Volunteers
No
Conditions
Interventions
Identification any tissue markers predictive or favoring early stenosis in AVF for haemodialysis.
Primary objective 1. Identify any predictive or favoring tissue markers of early stenosis in AVF for hemodialysis. Secondary objectives 2. Compare the results on the possible different expression of tissue markers before and during dialysis. 3. Compare the results on the possible different expression of tissue markers between AVFs made with portions of cephalic vein and AVFs made with portions of basilic vein, in order to evaluate whether the different topographic origin of the AVF can influence its duration.
Locations (1)
IRCCS AOU di Bologna Policlinico di Sant'Orsola
Bologna, Italy