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Comparison of Physiological Effects of Two Types of High-Flow Oxygen Therapy in Tracheostomized Patients
Sponsor: Jian-Xin Zhou
Summary
High-flow nasal oxygen therapy offers benefits like precise oxygen delivery, flow-related positive end-expiratory pressure generation and improved lung function. High-flow oxygen therapy can be applied via tracheostomy as high-flow tracheal oxygen. While high-flow tracheal oxygen has been used to facilitate weaning, it has diminished physiological effects due to bypassing upper airways. To enhance its effectiveness, researchers developed a modified high-flow tracheal oxygen tube with a smaller expiratory end diameter to increase airway resistance and pressure. This is a prospective randomized crossover study that aims to compare the physiological effects of standard and modified high-flow oxygen therapy in tracheostomized patients.
Official title: Comparison of Physiological Effects of Standard and Modified High-Flow Oxygen Therapy in Tracheostomized Patients
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2025-02-20
Completion Date
2025-12-30
Last Updated
2025-02-10
Healthy Volunteers
No
Conditions
Interventions
Modified high flow tracheal oxygen
Modified high-flow tracheal oxygen with flow rates of 40L/min and 60L/min will be performed.
Standard high flow tracheal oxygen
Standard high-flow tracheal oxygen with flow rates of 40 L/min and 60 L/min will be performed.
Locations (1)
Beijing Shijitan Hospital
Beijing, Beijing Municipality, China