Clinical Research Directory

Inclusion Criteria: * Signed informed consent form; * Male or female; * Age ≥ 18 years; * COVID-19 or influenza diagnosed by rapid test, with symptom onset less than 48 hours ago; * Clinical condition compatible with outpatient treatment. Exclusion Criteria: * Known hypersensitivity to nitazoxanide; * History of cardiomyopathies, hepatopathies, or nephropathies; * Antineoplastic treatment with chemotherapy or radiotherapy; * Severe autoimmune diseases with immunosuppression; * Transplant recipients; * Any uncompensated systemic disease at the investigator's discretion; * Participation in clinical studies in the last 12 months; * Pregnant or breastfeeding individuals; * Suspected bacterial coinfection or prescription of antibiotic therapy at enrollment; * Diagnosis of neurological disease (traumatic brain injury, stroke, Parkinson's disease, Alzheimer's disease, other dementias); * Diagnosis of developmental disorder (ADHD, ASD, learning disabilities, intellectual disability, Rett syndrome); * Significant hearing or vision impairment.