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Ischemic Stroke Nutrition Intervention Study
Sponsor: Harbin Medical University
Summary
The primary goal of this clinical trial is to assess whether vitamin K2 supplementation can effectively improve skeletal muscle and neurological function in patients with ischemic stroke. The main questions it aims to answer are: 1. Does supplementation with vitamin K2 improve the subjects' muscle strength and muscle mass? 2. Can supplementation with vitamin K2 improve the subjects' neurological function after a stroke? Researchers will compare vitamin K2 supplements with a placebo to observe whether vitamin K2 supplementation can improve skeletal muscle and neurological function in patients with ischemic stroke. Participants will: 1. Take vitamin K2 (MK-7) or a placebo daily for 1 year. 2. Attend face-to-face visits and provide biological samples and relevant data at 0, 3, 6, and 12 months. At 9 months, the visit will be online. After the intervention, follow-up will continue for 1 year to observe the long-term effects.
Official title: Health Effects of Vitamin K2 Supplementation on Skeletal Muscle and Neurological Function After Ischemic Stroke
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
190
Start Date
2025-03-23
Completion Date
2028-01-31
Last Updated
2026-03-03
Healthy Volunteers
No
Conditions
Interventions
Vitamin K2
Vitamin K2 (MK-7) 300µg/d for 1 year
Placebo
Placebo for 1 year
Locations (3)
The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China
Hongqi Hospital Affiliated to Mudanjiang Medical University
Mudanjiang, Heilongjiang, China
The Second Affiliated Hospital of Qiqihar Medical University
Qiqihar, Heilongjiang, China