Clinical Research Directory

Inclusion Criteria: * The patient: 1. Is ≥ 50 years old. 2. Has advanced PBK, with a best corrected visual acuity that lies between being able to see a hand move (i.e. 2 logMAR, included) and 2/10 excluded (i.e. 0.7 logMAR, excluded) and a central corneal thickness that exceeds 600 μm. 3. Is indicated for a corneal transplant. 4. Is pseudophakic. 5. Has provided free and informed written consent. 6. Is affiliated to a social security scheme. 7. Can be followed-up by the same investigating team during the study period. Exclusion Criteria: * The patient: 1. Has a history of corneal transplant on either eye (i.e. the study surgery will be the first corneal transplant for the patient). 2. Has an anterior chamber lens implant or is aphakic. 3. Has an ocular comorbidity that will impact visual acuity recovery: exudative or advanced atrophic AMD, advanced diabetic retinopathy (macular edema), advanced glaucoma (damage to the central visual field), important sequelae of central venous thrombosis of the retina or retinal detachment, previous amblyopia. 4. Has a contraindication to general anesthesia. 5. Is deprived of freedom, or under a legal protective measure. 6. Is included in another clinical study. 7. Has a severe general condition that might lead to premature discontinuation of the trial before the end of treatment period.