Clinical Research Directory

Inclusion Criteria: Women evaluated in the cardio-obstetrics clinic either prepartum, intrapartum, or postpartum with congenital heart disease. * Congenital heart disease: Based on modified World Health Organization (mWHO) classification of maternal cardiovascular disease group ≥ II. * mWHO Class I include mild pulmonary stenosis, uncomplicated patent ductus arteriosus, and repaired shunts, to be excluded. * mWHO Class II includes unoperated atrial septal defect or ventricular septal defect and repaired tetralogy of Fallot. * mWHO Class II-III includes mild left ventricular impairment, valvular heart disease not in class I, repaired aortic coarctation, Marfan without aortic dilation, bicuspid aortic valve with \<45 mm root, hypertrophic cardiomyopathy. * mWHO Class III includes systemic right ventricle, Fontan circulation, unrepaired cyanotic heart disease, Marfan with aorta 40-45 mm, bicuspid aortic valve with root 45-50 mm, other complex congenital heart disease (such as Shone complex). * mWHO Class IV includes Marfan with \>45 mm aorta, bicuspid aortic valve with \> 50 mm aorta, severe systemic ventricular dysfunction (EF\<30%), severe symptomatic AS or MS, native severe coarctation, all severe pulmonary hypertension patients from any cause. * Congenital valvular heart disease: * Native valvular heart disease: tricuspid, pulmonary, mitral and aortic with ≥ moderate regurgitation or stenosis by echocardiography. * Bioprosthetic valvular heart disease with ≥ moderate regurgitation or stenosis by echocardiography. * Any mechanical valve prosthesis * Congenital Cardiomyopathy * Cardiomyopathy with EF \< 30% * Cardiomyopathy with EF 30-50% * Provide Informed consent * Age \> 18 years of age Exclusion Criteria: * Patients on hemodialysis