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Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients
Sponsor: South Valley University
Summary
Mycobacterium leprae is a slow-growing bacillus that causes leprosy. the infection may take two to ten years to incubate. While the exact mechanism of infection transmission is unknown, direct bacillus absorption through the nasal or respiratory mucosa and aerosolized nasal secretions are the most common theories. The bacteria is subsequently transported by the bloodstream to the peripheral nerves, where it can result in tissue damage from painless burns and ulcers as well as irreparable nerve damage that results in a loss of protective feeling.
Official title: Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients and Its Relation to Multiple Drug Therapy: Randomized Clinical Trial
Key Details
Gender
All
Age Range
5 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-12-20
Completion Date
2025-12-20
Last Updated
2025-02-11
Healthy Volunteers
No
Conditions
Interventions
Dapsone
To evaluate the effect of the multi drug therapy in leprotic patients and their side effects and to assess the role of Rab 32 gene in leprosy prognosis and to know its association with the multi drug therapy.
Locations (1)
Qina University hospital, South Valley University Hospital
Qina, Egypt