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Indicators and Evaluation of Efficacy of Yin-nourishing and Fire-reducing Chinese Medicine for Girls With Rapid Progression of Early Puberty
Sponsor: Children's Hospital of Fudan University
Summary
1\. Evaluate whether AMH and SHBG have differential expression before and after the diagnosis of rapid and slow progression types of early puberty and whether this difference has a predictive effect on the rapid progression type. 2. Assess the therapeutic effect of nourishing yin and purging fire traditional Chinese medicine on girls with rapid progression type of early puberty providing a standardized clinical basis for the formulation of diagnostic and treatment guidelines (or protocols) for the rapid progression type of early puberty using traditional Chinese medicine
Key Details
Gender
FEMALE
Age Range
8 Years - 9 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2025-01-01
Completion Date
2026-02-28
Last Updated
2025-02-11
Healthy Volunteers
No
Conditions
Interventions
Xuandi Ziyin Mixture
Treatment is given only with the hospital preparation 'Xuandi Ziyin Mixture' with a dosage of 30ml per administration three times a day.
Locations (1)
Children's Hospital of Fudan University
Shanghai, Shanghai Municipality, China