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RECRUITING
NCT06822413

Raman Spectroscopy-Based Deep Learning Model for Early Pan-Cancer Early Diagnosis

Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

View on ClinicalTrials.gov

Summary

The goal of this observational study is to explore whether a Raman-based, deep learning-assisted approach can be used to develop an effective method for early pan-cancer screening. The study includes healthy individuals, patients at risk of cancer, and patients with diagnosed cancers. The main questions it aims to answer are: * Evaluating the deep-learning model's accuracy and specificity in identifying cancer-specific features in Raman spectral data and determining whether this method can accurately classify patients based on risk. * Identifying which model is more adaptable to the Raman spectrum * Providing an interpretable analysis of the model-generated diagnosis Participants are already being diagnosed and follow-up to determine the type of cancer.

Official title: A Novel Raman Spectroscopy-Based Method for Pan-Cancers Early Diagnosis Supported by Deep Learning: A Prospective, Single-Arm, Multicentre Study

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

600

Start Date

2022-09-01

Completion Date

2025-07-28

Last Updated

2025-04-24

Healthy Volunteers

Yes

Interventions

OTHER

No Interventions

All blood samples from participating patients were obtained from routine clinical blood tests conducted during hospital admission or other necessary medical evaluations, followed by serum extraction.

Locations (4)

The First Affiliated Hospital to Nanchang University

Nanchang, Jiangxi, China

The Second Affiliated Hospital to Nanchang University

Nanchang, Jiangxi, China

Huashan Hospital Affiliated to Fudan University

Shanghai, Shanghai Municipality, China

The Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China