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A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial
Sponsor: Fred Hutchinson Cancer Center
Summary
This clinical trial studies whether an intervention that addresses two or more levels of care (multilevel intervention) increases follow-up of abnormal, non-invasive, colorectal cancer (CRC) screening test results. The fecal immunochemical test (FIT) is a non-invasive, stool-based, CRC screening test. FITs are relatively inexpensive and can be completed at home, for these reasons, it is a preferred method of CRC screening in healthcare settings that care for under-resourced patients or have limited colonoscopy access. For FIT-based CRC screening to be effective, abnormal results must be followed by a colonoscopy, however many patients fail to complete this recommended follow-up test. The multilevel intervention addresses barriers to follow-up colonoscopy at the patient and health system levels of care through a CRC screening patient navigator, an educational video, and transportation assistance. The navigator provides patient support and assistance with colonoscopy scheduling. The educational video addresses identified patient fears around colonoscopies. Transportation assistance is offered after the colonoscopy through a rideshare program to address transportation barriers. Therefore, this multilevel intervention may increase follow-up colonoscopy completion in patients with abnormal FIT results.
Official title: PROACT: Promoting Follow-Up of Abnormal Colorectal Cancer Screening Tests Through Multilevel Interventions
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
682
Start Date
2025-12-16
Completion Date
2029-11-30
Last Updated
2026-02-17
Healthy Volunteers
Yes
Conditions
Interventions
Best Practice
Receive usual care CRC screening program navigation
Educational Intervention
Receive QR code and link to video addressing fears of colonoscopy
Electronic Health Record Review
Ancillary studies
Interview
Ancillary studies
Supportive Care
Receive rideshare transportation home after colonoscopy
Survey Administration
Ancillary studies
Locations (1)
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States