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Long-Term Evaluation of TAILORED Vs Anatomical Ablation Strategy for Persistent Atrial Fibrillation
Sponsor: Volta Medical
Summary
The TAILORED-LT study is conducted as an extension follow-up until 5 years of the initial TAILORED-AF study (NCT04702451), in order to demonstrate the long-term superiority in terms of freedom of atrial fibrillation (AF) of a tailored ablation strategy targeting areas of spatio-temporal dispersed electrograms in combination with pulmonary veins isolation (PVI) over an anatomical ablation strategy targeting PVI alone for the initial ablation procedure of persistent AF.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
278
Start Date
2025-03-06
Completion Date
2027-12-31
Last Updated
2025-03-13
Healthy Volunteers
No
Conditions
Interventions
Volta AF-Xplorer
Dispersion ablation strategy guided by Volta Medical AI-software targeting areas of spatiotemporal dispersed electrograms
Dispersion ablation + PVI
TAILORED-AF index procedure: Dispersion ablation + PVI
PVI
TAILORED-AF index procedure: PVI only
Locations (13)
CHU Lyon, Hôpital Louis Pradel
Bron, France
Pôle Santé République
Clermont-Ferrand, France
Hôpital Saint Philibert
Lomme, France
Hôpital Saint-Joseph Marseille
Marseille, France
Hôpital Privé Jacques Cartier
Massy, France
Hôpital Privé du Confluent
Nantes, France
Polyclinique Saint George
Nice, France
Centre Cardiologique du Nord
Saint-Denis, France
Clinique Rhéna
Strasbourg, France
Clinique Pasteur
Toulouse, France
CHRU Nancy, Institut Lorrain du coeur et des vaisseaux
Vandœuvre-lès-Nancy, France
Klinikum Coburg
Coburg, Germany
German Heart Center
Munich, Germany