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The Effect of Hydration on Postprandial Metabolic Responses
Sponsor: Loughborough University
Summary
Certain populations, such as industrial workers and endurance athletes are particularly susceptible to dehydration due to exposure to heat for long periods of time causing evaporative water loss via sweating. The physical and cognitive decrements associated with dehydration have been widely researched, however the effect of dehydration on metabolism is lesser known. As climate change is causing temperatures to rise, and metabolic diseases such as type 2 diabetes are more common, the effect of dehydration on metabolism, specifically glycemic response to meals, needs to be established for future recommendations in clinical, environmental and athletic settings. Therefore, the aim of this study is to investigate the effect of acute exercise-induced dehydration on subsequent metabolic responses to feeding (i.e. glycaemia and insulinaemia).
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
16
Start Date
2025-03
Completion Date
2025-12
Last Updated
2025-02-13
Healthy Volunteers
Yes
Conditions
Interventions
Water intake
Water ingested to fully replace sweat losses during exercise.
Water restriction
Water restriction to induce hypohydration of \~3% body mass through sweat losses during exercise.
Locations (1)
Loughborough University
Loughborough, Leicestershire, United Kingdom