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RECRUITING
NCT06827249
NA

Peginterferon α-2b Injection for the Treatment of Pediatric RSV Bronchiolitis

Sponsor: Children's Hospital of Soochow University

View on ClinicalTrials.gov

Summary

This is a multicenter, randomized, positive-controlled, non-inferiority clinical study, planning to enroll 90 children with bronchiolitis caused by respiratory syncytial virus infection, to evaluate the safety and efficacy of inhaled Peginterferon α-2b injection compared to recombinant human interferon α2b in the treatment of pediatric respiratory syncytial virus bronchiolitis.

Official title: A Multicenter, Randomized, Positive-controlled, Non-inferiority Clinical Study to Evaluate the Safety and Efficacy of Peginterferon α2b Injection in the Treatment of Pediatric RSV Bronchiolitis

Key Details

Gender

All

Age Range

6 Months - 2 Years

Study Type

INTERVENTIONAL

Enrollment

90

Start Date

2025-03

Completion Date

2027-06

Last Updated

2025-02-14

Healthy Volunteers

No

Conditions

Interventions

DRUG

Peginterferon α-2b injection

Peginterferon α-2b injection, 90 mcg, on the basis of conventional treatments such as asthma control, oxygen inhalation, and fluid replacement, nebulized inhalation using air compression or oxygen-driven methods is administered on days 1, 3, and 5, once a day.

DRUG

Recombinant Human Interferon α2b

Recombinant Human Interferon alpha 2b, at a dose of 100,000 IU/kg, based on the conventional treatments such as asthma control, oxygen inhalation, and fluid replacement, will be administered via nebulized inhalation using air compression or oxygen-driven methods from day 1 to day 5, twice daily.

Locations (3)

Wuhan Women and Children's Health Care Center

Wuhan, Hubei, China

Children's Hospital of Soochow University

Suzhou, Jiangsu, China

The First Hospital of Jilin University

Changchun, Jilin, China