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Recording Cutaneous Vagal Nerve Activity With Multi-Electrode Array (MEA) in Patients Undergoing VNS Therapy
Sponsor: Indiana University
Summary
The overall purpose of the ABVN Phase 2 grant is to expand on previous work evaluating vagal nerve function. This will be accomplished through several independent, but related, studies. The purpose of this study is to find out if it is possible to record compound nerve action potentials through the skin surface from participants who have previously had a vagus nerve stimulation device implanted as part of clinical care.
Official title: Effect of Electrical Stimulation of the Auricular Branch of the Vagus Nerve (ABVN) on Cervical Vagus Nerve Action Potentials - Phase 2
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
22
Start Date
2021-05-26
Completion Date
2022-07-13
Last Updated
2026-10-14
Healthy Volunteers
No
Conditions
Interventions
Multi-Electrode Array (MEA) Recording
Cervical neck electrodes used in this part of the study will include the multi electrode array (MEA). The MEA can be placed on either side of the neck over the area of the vagus nerve to record any electrical activity that might occur during the baseline period. Additionally, two ECG electrodes are placed either one on each arm or on the chest for measurement of the electrocardiogram (ECG). Three ECG electrodes are placed on the abdomen in a line parallel to the longitudinal axis of the stomach to record the electrogastrogram (EGG). A onetime baseline recording will be made for 20 minutes after which the subject will be discharged from the study.
Locations (1)
Indiana University Hosptial
Indianapolis, Indiana, United States