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Epigenetic and Neurochemical Correlates of Bipolar Disorder
Sponsor: Assiut University
Summary
Aim of Study: * To assess DNA methylation of the IL1-B gene in individuals with BD compared to healthy controls. * To evaluate the expression of 5-hydroxytryptamine (serotonin) receptors in BD and shed more light into its role into the pathophysioogy of BD. * To measure differences of glutamic acid levels between study groups. * To investigate correlations between these biomarkers among study groups, and their alignment with clinical presentations.
Official title: Epigenetic and Neurochemical Correlates of Bipolar Disorder: Investigating Key Biomarkers
Key Details
Gender
All
Age Range
18 Months - 45 Months
Study Type
OBSERVATIONAL
Enrollment
108
Start Date
2025-03-01
Completion Date
2026-04-30
Last Updated
2025-02-17
Healthy Volunteers
Yes