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Tailored One Anastomosis Gastric Bypass
Sponsor: Tel-Aviv Sourasky Medical Center
Summary
One Anastomosis Gastric Bypass (OAGB) is the most common metabolic and bariatric surgery (MBS) in Israel, recognized for its effectiveness in achieving sustainable weight loss and mitigating obesity-related diseases. The metabolic outcomes of OAGB are significantly influenced by the length of the biliopancreatic limb (BPL). The objective of this study is to determine whether tailoring the BPL length to the total small bowel length (TSBL) results in more effective weight loss compared to patients undergoing OAGB with a fixed BPL of 180 cm. Efficacy and safety of this approach will also be evaluated, ensuring it does not lead to long-term morbidity or negatively impact patients' quality of life.
Official title: Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2025-01-29
Completion Date
2029-01-31
Last Updated
2025-07-24
Healthy Volunteers
No
Conditions
Interventions
Tailored BPL length
Total bowel length measure and BPL will be 40% of total bowel length ensuring at least 250 cm common channel
Control - BPL 180 cm
Total bowel length measure and BPL will be180 cm
Locations (1)
Tel Aviv Sourasky Medical Center
Tel Aviv, Israel