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Somatostatin Receptor PET Imaging to Guide Radiotherapy Dose Escalation in High Risk Meningiomas.
Sponsor: Centro di Riferimento Oncologico - Aviano
Summary
High-risk meningiomas always require postsurgical radiation treatment. Recent evidence has shown that increased radiation therapy dose may be associated with increased intracranial control of disease. In order to better define the volume of radiation treatment, the addition of PET imaging with somatostatin receptor tracers adds additional information compared to encephalon MRI with MoC alone.The present study aims to investigate whether radiation treatment with higher doses than the standard and defined using PET imaging can be safe and at the same time effective in order to increase progression-free survival in high-risk meningiomas.
Key Details
Gender
All
Age Range
16 Years - Any
Study Type
INTERVENTIONAL
Enrollment
53
Start Date
2024-12-23
Completion Date
2037-12-23
Last Updated
2025-02-17
Healthy Volunteers
No
Conditions
Interventions
Dose escalation of radiation therapy, based on somatostatin receptor PET imaging
Radiation treatment with higher doses than the standard and defined using PET imaging
Locations (1)
Centro di Riferimento Oncologico di Aviano (CRO)
Aviano, Pordenone, Italy