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The ROAR Study: Reactive Oxygen Species and Reproduction
Sponsor: University of California, San Francisco
Summary
This is a prospective cohort study characterizing follicular fluid and serum levels of oxidative stress in women with various infertility diagnoses undergoing in vitro fertilization, and assessing the relationship of oxidative stress to oocyte competence as determined by embryo development outcomes. Furthermore, we will measure oxidative stress in sperm and correlate the overall oxidative stress within the couple with IVF and pregnancy outcomes of the resultant embryos.
Key Details
Gender
All
Age Range
18 Years - 43 Years
Study Type
OBSERVATIONAL
Enrollment
1100
Start Date
2025-07-07
Completion Date
2027-03-01
Last Updated
2026-02-17
Healthy Volunteers
Yes
Conditions
Interventions
Oxidative stress markers
We will measure markers of oxidative stress in the follicular fluid, semen, and blood and correlate this with IVF and reproductive outcomes
Locations (1)
University of California, San Francisco
San Francisco, California, United States