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Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response
Sponsor: University Health Network, Toronto
Summary
This prospective, single-arm feasibility study will include patients with prostate cancer that have controlled local disease diagnosed with oligorecurrent para-aortic nodal disease and/or common iliac nodal disease detected by PSMA PET or conventional CT/MRI imaging, and these patients will undergo CT-guided online adaptive SBRT to the tumor and elective SBRT to adjacent at-risk nodal regions.
Official title: A Phase I, Prospective, Single-Arm Feasibility Study: Elective Adaptive Radiation With SBRT for Improved DurabilitY of Response (EASY)
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
26
Start Date
2026-07-07
Completion Date
2029-07-07
Last Updated
2026-03-23
Healthy Volunteers
No
Conditions
Interventions
Adaptive radiotherapy using SBRT
Adaptive External beam radiotherapy using SBRT 30-40Gy to the tumor nodal GTV volume(s) plus 25 Gy in 5 fractions ENI to PA nodes (+ common iliac nodes)
Locations (1)
Princess Margaret Cancer Centre
Toronto, Ontario, Canada