Clinical Research Directory

Inclusion Criteria: 1. Healthy adult males and/or females, 18 to 45 years of age (inclusive) at the date of signed consent form. 2. Body mass index (BMI) greater than or equal to 18 and less than 32 (kg/m2) and a minimum body weight of 45 kg. 3. Able to participate and comply with all study procedures and restrictions, and willing to provide written informed consent to participate in the study. 4. Women of child-bearing potential and sexually active males willing to use highly effective methods of contraception from screening until 3 months after last dose of study drug. In addition, participants must not donate sperm/egg for the time period specified above. Exclusion Criteria: 1. History of disease of ocular surface, fundus, central nervous system, psychiatric and psychological condition, cardiovascular system, kidney, liver, digestive system, respiratory system, or metabolic/endocrine system, or other disease that in the opinion of the Investigator (or medically qualified designee) may make participation unsafe for the participant or interfere with study evaluations. 2. Any abnormal examination with clinical significance may interfere with study evaluations in opinion of the Investigator (or medically qualified designee). 3. History of eye trauma or surgery including LASIK/LASEK. 4. Any corrected visual acuity \< 20/20, or intraocular pressure ≥ 21 mmHg. 5. Clinically significant abnormalities on ophthalmic examination that would hinder the assessment of the eye or data collection at the discretion of the Investigator and/or ophthalmologist (or medically qualified designee).