Clinical Research Directory

Inclusion Criteria for patient group: 1. Diagnosed with CRS based on the diagnostic criteria of the EPOS guideline. 2. Provision of signed and dated informed consent form. 3. Patients with CRS admitted to the hospital awaiting endoscopic sinus surgery. Inclusion Criteria for control group: 1. Healthy controls undergoing surgery for the deviated septum. 2. Provision of signed and dated informed consent form. Exclusion Criteria for patient group: 1. Those who have taken oral glucocorticoids, antibiotics, anti-leukotrienes, and antihistamines within four weeks. 2. Patients who have had prior sinus surgery. 3. Patients with fungal sinusitis, inverted papilloma, or other nasal diseases. 4. Patients with a diagnosis of immune suppression or suspicion of malignancy that may be affecting the nose/paranasal sinuses. 5. Patients who are mentally or physically unable to perform olfactory tests Exclusion Criteria for control group: 1. Patients with nasal polyps, sinusitis, nasal cavity tumors and other diseases. 2. Patients with hyposmia or anosmia. 3. Patients with diagnosed neurodegenerative disease. 4. Patients who are mentally or physically unable to perform olfactory tests.