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Biomarkers for Cognitive Decline in Intracerebral Hemorrhage
Sponsor: Rush University Medical Center
Summary
The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are * if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests Participants will undergo * cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH
Official title: Silent Brain Infarcts in Spontaneous Intracerebral Hemorrhage as a Prognostic Biomarker for Vascular Contributions to Cognitive Impairment and Dementia (VCID)
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
OBSERVATIONAL
Enrollment
118
Start Date
2025-08-02
Completion Date
2029-08-01
Last Updated
2025-08-08
Healthy Volunteers
No
Conditions
Interventions
MRI
MRI during hospitalization and at 12 months post sICH
Blood Draw
Will occur during hospitalization and at 3, 6 and 12 months post sICH
Cognitive Test
Cognitive testing will occur during hospitalization and at 3, 6 and 12 months post sICH
Locations (1)
Rush University Medical Center
Chicago, Illinois, United States