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ENROLLING BY INVITATION
NCT06836531

POCT Detection for Blood Concentration of Tirofiban in Acute Myocardial Infarction Based on Azo-POP Probe.

Sponsor: First Affiliated Hospital of Ningbo University

View on ClinicalTrials.gov

Summary

The goal of this observational study is to monitor blood drug concentration during the use of tirofiban, predict the occurrence of intraoperative and postoperative complications related to interventional therapy, and evaluate the efficacy of multiple antiplatelet drugs.The main question it aims to answer is: 1. If the POCT detection technology for blood concentration of tirofiban based on portable mass spectrometer can be used for on-site sampling, clinical testing, and immediate analysis next to patients undergoing coronary intervention therapy. 2. LC-MS/MS untargeted metabolomics analysis techniques combined with machine learning algorithms will be used to screen biomarkers for myocardial infarction.

Official title: POCT Detection for Blood Concentration of Tirofiban in Acute Myocardial Infarction Based on Azo-POP Probe, and Use Metabolomics Analysis Combined with Machine Learning Algorithms for Screening Biomarkers of Myocardial Infarction.

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2025-03-30

Completion Date

2025-07-31

Last Updated

2025-03-25

Healthy Volunteers

Yes

Locations (1)

First Affiliated Hospital of Ningbo University

Ningbo, Zhejiang, China