Clinical Research Directory
Browse clinical research sites, groups, and studies.
The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRS
Sponsor: Peking University Third Hospital
Summary
The goal of this clinical trial is to validate the effectiveness of the modified olfactory training device, the main questions it aims to answer are: Is it possible that the device can treat postoperative olfactory dysfunction in patients with chronic sinusitis? Compared to the conventional device, how efficient is the modified olfactory training device for treating postoperative olfactory dysfunction in patients with chronic sinusitis?
Official title: Protocol for a Randomized Controlled Trial Evaluating the Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With Chronic Rhinosinusitis
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
213
Start Date
2025-03-14
Completion Date
2027-03-14
Last Updated
2025-02-20
Healthy Volunteers
No
Interventions
Conventional olfactory training device
Four odorants are used: phenyl ethyl alcohol (PEA): rose, menthol: mint, citronellal: lemon, and eugenol: cloves. Training patients will receive four glass vials. Each contains one odorant (5 mL, soaked in cotton pads to prevent spilling) and is labeled with the name of the odorant. Budesonide irrigation can effectively target the olfactory cleft area to provide anti-inflammatory effects.
Modified olfactory training device
The modified olfactory training device is based on the nasal bidirectional drug delivery system. The device uses breathing pressure to create positive pressure, significantly increasing the deposition rate of odors in the olfactory cleft area. Budesonide irrigation can effectively target the olfactory cleft area to provide anti-inflammatory effects.
Budesonide irrigation
Budesonide irrigation can effectively target the olfactory cleft area to provide anti-inflammatory effects.
Locations (1)
Beijing
Beijing, Beijing Municipality, China