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Predictors of Bone Mineral Density in Lupus Nephritis Activity
Sponsor: Assiut University
Summary
Our aim in this study is Correlation of histopathology of renal biopsy in SLE with lupus nephritis patients versus predictors of bone mineral density in active and inactive lupus nephritis
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-04-01
Completion Date
2027-05-01
Last Updated
2025-02-20
Healthy Volunteers
No
Interventions
fibroblast growth factor 23
Investigations: including the different following modalititis A. Laboratory investigations include: 1. Complete blood picture, PT PC INR, RBS Kidney function tests, eGFR Urine analysis, 24 hours' protein in urine 2. Specific laboratory investigations for SLE and lupus nephritis: ANA,AntiDsDNA,C3,C4 3. Laboratory investigations of Bone mineral density predictors Ca, phosphorus, PTH, vitamin D (OH), Alkaline phosphatase, Fibroblast Growth Factor 23 (FGF 23) B. Imaging studies: 1 - Abdominal ultrasound 2- chest x-ray 3- Echocardiography (in lupus nephritis with activity form) 4- DEXA bone scan C. Invasive modality: Renal biopsy of Patients with SLE with lupus nephritis