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Methadone Dose Monitoring With a Remote Medication Monitor
Sponsor: Cari Health Inc.
Summary
Proof of concept: Pilot Study A Pilot, proof of concept, observational study with a long-term goal to develop a minimally invasive wearable Remote Medication Monitor (RMM) that provides continuous, real-time data on methadone levels in interstitial fluid (ISF). An RMM could be used as a medication adherence monitor and would allow for the physician, counselor, patient, or family member to remotely verify that a physician-prescribed dose has been taken.
Official title: Assessment of Methadone Dose Taken
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2025-04-26
Completion Date
2025-06
Last Updated
2025-02-20
Healthy Volunteers
No
Conditions
Interventions
Measurement of Methadone in the Interstitial Fluid (ISF) before and after prescribed dose taken ex vivo
Measurement of Methadone and its metabolites in interstitial fluid with Liquid Chromatography - Mass Spectroscopy (LC-MS) and Aptamer based Assay
Measurement of Methadone in the Interstitial Fluid before and after prescribed dose taken in vivo
Measurement of Methadone and its metabolites in ISF with LC-MS and RMM
ISF Extraction Device 2
Up to 15 minute periods of continuous ISF collection for analysis
Locations (1)
Synergy
Lemon Grove, California, United States