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Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography
Sponsor: Centre Hospitalier William Morey - Chalon sur Saône
Summary
29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality. It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias. The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
60
Start Date
2024-06-03
Completion Date
2027-12
Last Updated
2026-03-18
Healthy Volunteers
No
Interventions
OCT-BIO-KTA cohort
Dynamic full-field optical coherence tomography (D-FF-OCT) analysis of arterial catheter sections before microbiological analysis of catheter biofilm
Locations (2)
CHU Dijon Bourgogne
Dijon, Bourgogne-Franche-Comté, France
CH Macon
Mâcon, Bourgogne-Franche-Comté, France