Clinical Research Directory

Inclusion Criteria: * Male or female 18 to 65 years of age at the time of consent(cutoff value included). * Body mass Index(BMI)≥28 kilograms per square meter(kg/m2),or ≥24 kg/m2 and previous diagnosis with at least one of the following comorbidities: prediabetes, hypertension, dyslipidemia, non-alcoholic fatty liver disease, obstructive sleep apnea. * Weight change ≤5.0% after diet and exercise control for at least 12 weeks before screening. Exclusion Criteria: * Diabetes mellitus * Weight change \>5.0% after diet and exercise control for at least 12 weeks before screening * Have used or are currently using weight loss drugs within 3 months before screening * History of pancreatitis * Family or personal history of medullary thyroid carcinoma(MTC)or multiple endocrine neoplasia syndrome type 2(MEN-2) * History of moderate to severe depression, or have a history of serious mental illness * Any lifetime history of a suicide attempt * Have a history of significant atopy (severe allergic manifestations), multiple or severe drug allergies, or severe posttreatment hypersensitivity reactions * Have a history of any malignancy within the past 5 years