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Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease
Sponsor: Zhang longjiang,MD
Summary
The primary objective of this study is to evaluate whether a management strategy based on coronary computed tomography angiography (CCTA) for patients with non-obstructive coronary artery disease can improve the LDL-C target achievement rate compared to a traditional management strategy without follow-up CCTA, thereby reducing the incidence of major adverse cardiovascular and cerebrovascular events over a 3 years period, including all-cause mortality, myocardial infarction, ischemia driven revascularation and stroke.
Official title: Serial Coronary CTA-based Plaque Progression Detection for Management of Coronary Heart Disease: a Randomised Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
3100
Start Date
2025-02-28
Completion Date
2028-12-30
Last Updated
2026-03-24
Healthy Volunteers
No
Conditions
Interventions
Coronary Computed Tomography Angiography
Based on the assessment of plaque progression after follow-up CCTA examination, patients will be given either intensive treatment or routine treatment.
Current clinical guidelines
Patients will be treated according to the 2024 ESC Guidelines for the Management of Chronic Coronary Syndromes.
Locations (1)
Research Institute Of Medical Imaging Jinling Hospital
Nanjing, Jiangsu, China