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RECRUITING
NCT06843525

Bite Force Measurements

Sponsor: Rutgers, The State University of New Jersey

View on ClinicalTrials.gov

Summary

ABSTRACT: Acute dental pain from untreated decay often drives patients to emergency rooms (ERs), where the lack of definitive dental treatment results in nearly 75% of these patients receiving analgesics, predominantly opioids. Addressing the need for non-opioid pain alternatives is crucial. Emerging evidence suggests that dental pain from pulpal and periodontal conditions (affecting the tooth's nerve and surrounding tissues) involves neuropathic mechanisms, such as mechanical allodynia (MA) and central sensitization (CS). These mechanisms can amplify pain perception, causing typically non-painful actions, like chewing, to become painful and resulting in hypersensitivity extending beyond the affected tooth. Reliably identifying these mechanisms with quantitative measures can support improved pain assessment and targeted non-opioid treatment. This minimally invasive prospective cohort study will use the FDA-approved Innobyte® device, a precise bite-force measurement tool, to evaluate periodontal health and to quantify mechanical pain thresholds in patients requiring endodontic treatment (root canal therapy).

Official title: Exploring a Neuropathic Basis for Acute Pulpal Pain- a Clinical Pilot

Key Details

Gender

All

Age Range

18 Years - 89 Years

Study Type

OBSERVATIONAL

Enrollment

112

Start Date

2025-05-16

Completion Date

2026-11-01

Last Updated

2025-07-24

Healthy Volunteers

No

Locations (1)

Rutgers School of Dental Medicine

Newark, New Jersey, United States