Clinical Research Directory

Inclusion criteria: 1. Age 20-45 years old; 2. Premenopausal women whose thyroid B-ultrasound + surgical pathology is clearly differentiated thyroid cancer (papillar thyroid cancer or follicular thyroid cancer); 3. TNM stage is in stage I (T1-3, N0 or N1, M0); 4. Treatment of thyroid tumor resection: unilateral lobe of the thyroid + isthmus resection, total thyroidectomy, total thyroidectomy + RAIT. Exclusion criteria: 1. Patients with malignant tumors in other parts or low undifferentiated thyroid cancer; 2. Patients with abnormal liver and kidney function; 3. TNM stage II and above; 4. History of ovarian surgery, hysterectomy, pelvic surgery or radiation therapy; 5. Pregnancy; 6. Have the following uterine abnormalities, such as uterine malformation (single-horned uterus, double uterus); untreated mediastinal uterus, submucosal uterine fibroids, multiple endometrial polyps, or severe uterine adhesion. 7. Patients diagnosed with polycystic ovary syndrome by the Rotterdam standard; 8. Patients with ovarian failure; 9. Patients have infectious factors, immune diseases and metabolic diseases that may affect pregnancy outcomes; 10. Pregnancy contraindications or diseases that have a clear impact on pregnancy.