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RECRUITING
NCT06845722
NA

Combined Effects of Balance and Cognitive Training in Patients With Multiple Sclerosis

Sponsor: Riphah International University

View on ClinicalTrials.gov

Summary

Multiple sclerosis is a potentially disabling disease of the brain and spinal cord involving the central nervous system. Multiple Sclerosis can cause balance and cognitive impairment in patients, affecting overall quality of life. Balance and cognitive training can effectively improve the overall executive function and mobility in patients with multiple sclerosis.

Official title: Combined Effects of Balance and Cognitive Training on Executive Functions, Balance and Quality of Life in Patients With Multiple Sclerosis

Key Details

Gender

All

Age Range

40 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

42

Start Date

2024-10-01

Completion Date

2025-05-02

Last Updated

2025-02-25

Healthy Volunteers

No

Interventions

OTHER

Balance training

* The balance training will be given for 12 weeks (2 sessions/week, 30-35 in each) that included six balance exercises per training session. * After 5-min warm-up program including general (e.g., neck rolls, shoulder circles, side bends, hip circles, marsh in place) and specific (e.g., two-/one-legged stance on unstable devices, forward/backward beam walking). * Two sets per balance exercise will be performed for 30s each with a 60s rest period between sets and a 90 s break between exercises. Yet, both groups will execute the same training volume (i.e., number of exercises, number of sets per exercise, and duration per set of exercise). * Progression during training will be achieved by means of increasing exercise duration (i.e., from 30s over 45s to 60 s), change of stance (i.e., two-legged stance, tandem. stance, one-legged stance) and walking (i.e., forward, backward) condition, manipulation of visual input (e.g., eyes opened vs. closed), and concurrent execution of cognitive

OTHER

Cognitive Rehabilitation:

* The cognitive rehabilitation will be given for 12 weeks ( 2 sessions/week,30 min each session). The individual sessions for the CR approach will involve an individualized intervention focusing on a personally meaningful goal (e.g., maintaining attention while flipping cards and finding matching pairs, learning to use a cellular phone, remembering the names of people). * The individual sessions will be consisted of practical strategies and aids, compensation strategies (e.g., using a memory notebook), and the techniques for stress management to improve performance and functioning in relation to goals. The group sessions of CR involved some tasks of cognitive training. * The group sessions will be focused on practicing time-and-place orientation through paper-and pencil tasks provided by a therapist and use of a calendar and personal memory notebook or cellular phone at the start of each session. (30) * The group sessions also involved matching faces and names and learning memory

Locations (1)

Jinnah Hospital

Lahore, Pakistan