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Second-Look Ultrasound Post Contrast-Enhanced Mammography for Additional Lesions Characterization
Sponsor: Graziella di Grezia
Summary
This study investigates the utility of second-look ultrasound (US) following contrast-enhanced mammography (CEM) to characterize additional lesions detected during routine breast imaging.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
350
Start Date
2025-01-01
Completion Date
2026-01-31
Last Updated
2025-02-26
Healthy Volunteers
No
Interventions
CEM protocol
The intervention consists of Second-Look Ultrasound (SLUS) performed following Contrast-Enhanced Mammography (CEM) to further evaluate additional lesions detected during routine breast imaging. When CEM identifies additional or suspicious lesions not clearly characterized by mammography alone, targeted ultrasound is conducted to assess lesion morphology, vascularity, and acoustic characteristics. Radiologists with expertise in both CEM and ultrasound interpretation will perform SLUS to determine whether the lesions require biopsy, short-term follow-up, or no further action. Findings will be correlated with histopathological results (if biopsy is performed) or follow-up imaging to assess diagnostic accuracy.
Locations (1)
University of Campania Luigi Vanvitelli
Naples, Italy