Clinical Research Directory
Browse clinical research sites, groups, and studies.
Unbound Cloxacillin Concentrations During Continuous Infusion
Sponsor: Emeli Månsson
Summary
Cloxacillin is the first-line choice for the treatment of severe infections caused by the bacterium Staphylococcus aureus in Sweden. Over the past year, cloxacillin is increasingly administred through continuous infusion. In this study, the free (unbound) concentration of cloxacillin when administered as a continuous infusion will be measured to ensure that the free concentration is neither too high nor too low. A PK/PD model will be developed to predict which dosage of cloxacillin is appropriate for an individual based on age, gender, kidney function, and serum-protein level.
Official title: Concentration of Unbound Cloxacillin in Adults Treated With Continuous Infusion Via Elastomeric Pump
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
25
Start Date
2026-01-14
Completion Date
2027-12
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
Unbound cloxacillin concentration
Unbound cloxacillin concentration measured at baseline, after 4h, after 24h and after 48h of continuous infusion.
Locations (1)
Västmanlands sjukhus Västerås
Västerås, Sweden