Clinical Research Directory

Inclusion Criteria: The subject selection will be according to the following criteria: 1. Ages of patients will be ranged from 20 to 35 years. 2. All patients underwent severe burn with TBSA ranged from 20% to 35%. 3. 8 th to 16th week post burn. 4. All patients will be referred with persisted anemia by a surgeon before starting the study procedure. 5. All patients will enter the study having their informed consent Exclusion Criteria: The potential participants will be excluded if they meet one of the following criteria: 16 1. Patients with persisted pre burn anemia associated with systematic chronic disease such as coronary artery disease or chronic kidney disease. 2. Patients with pre burn persisted anemia associated with autoimmune disease such as Rheumatoid arthritis, Systemic lupus erythematosus ,Vasculitis, Sarcoidosis, Inflammatory bowel disease (IBD). 3. Unevaluated cardiac arrhythmia, Chronic bronchitis, poorly controlled type 1 diabetes, Extreme morbid obesity, Extreme underweight body mass index less than 12, Poorly controlled hypertension, Poorly controlled seizure disorder, Poorly controlled hyperthyroidism, Orthopedic limitation as fracture, .