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RECRUITING
NCT06850038

A Study Observing the Long-term, Effectiveness and Safety of Odevixibat (Bylvay) in Patients With Alagille Syndrome (ALGS) Who Are Receiving Ongoing Treatment

Sponsor: Ipsen

View on ClinicalTrials.gov

Summary

This study will collect information from patients with Alagille syndrome (ALGS) as they use odevixibat (Bylvay) in their daily lives. Odevixibat is a medicine that helps patients with ALGS, a rare disease that harms their liver and causes itching. The main aim of this study is to observe the long-term, everyday effectiveness and safety of the drug odevixibat in patients with ALGS who are receiving ongoing treatment.

Official title: Prospective Registry-Based Study Evaluating the Effectiveness and Safety of Odevixibat in Participants With Alagille Syndrome (ALGS)

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

30

Start Date

2025-04-22

Completion Date

2029-11

Last Updated

2026-04-01

Healthy Volunteers

No

Locations (9)

Childrens Hospital Los Angeles

Los Angeles, California, United States

UCSF Pediatric Gastroenterology

San Francisco, California, United States

The Children's Mercy Hospital

Kansas City, Missouri, United States

St Louis University. SSM Cardinal Glennon Childrens Medical Center

St Louis, Missouri, United States

Columbia University

New York, New York, United States

NYU Langone - NYU Grossman School of Medicine

New York, New York, United States

Le Bonheur Children's Hospital

Memphis, Tennessee, United States

UT Southwestern Childrens Medical Center

Dallas, Texas, United States

Proactive El Paso,LLC

El Paso, Texas, United States